Medical and health_Latest Science Articles

Location: Home > Medical and health >

Insulin Intensive Treatment on Hyperproteolysis of Skeletal Muscle in Burned Sepsis

Sepsis in severely burned patients is associated with high morbidity and mortality. It is well known that hypermetabolism and negative nitrogen balance invariably accompanies sepsis, and the process has been labeled as self-cannibalistic. Fo....
The Difference Expression of Rat Hepatic Lipid Metabolism Related Genes in Response to Burn Wound Sep

Wound sepsis remains to be the leading cause of death in critically burned patients. Studies have shown that almost all the septic patients have hypermetabolism which contributes to the development of multiple organs dysfunction syndrome (MO....
The Effects of Calcium Antagonist Verapamil in the Murine Model of Traumatic Hemorrhagic Shock with E

Objective: This study is designed to evaluate the effects of calcium antagonist verapamil in the murine model of traumatic hemorrhagic shock with endotoxemia and to investigate the changes of phosphorylated form of p38MAPK in macrophages.Met....
Study on the Influence of Recombinant Human Growth Hormone on the Intestinal Mucosal Barrier and Gut

ObjectiveSevere burn, trauma, shock ,infection, major operation and other pathological factors can all lead to intestinal mucosal barrier dysfunction,intestinal flora ecosystem imbalance and the immune dysfunction which may induce bacteria/e....
Isolation, Cultivation of Human Fetal Sebocytes and Sweat Eccrine Gland Cells in Vitro, and the Preli

[Background]The local or general lesions after burns are related to the loss of skin barrier, so the main purpose of burns therapy is to heal the burns wound as early as possible, and restore the function and appearance of the burned skin as....
The Epidemiological Research on Traffic Injuries on Shenyang-Dalian Expressway

ObjectiveThrough the investigation into traffic accidents on Shenyang — Dalian expressway ( Shen - Da expressway for short) during the twelve years, to extract the distribution characteristics in time, locations, personnel, vehicles, wound....
Study on Trauma Severity Score Method Based on ICD

Trauma score, as an important tool for injury treatment supporting and a key branch of trauma research, is more and more concerned by people in trauma field world wide. More and more researches on trauma score methods have been carried out a....
Experimental and Clinical Research of Simultaneous Pancreas-kidney Transplantation with Enteric Drain

Part 1 Establishment of the Model of Simultaneous Pancreas-kidney Transplantation with Enteric Drainage and Systemical Venous Drainage or Portal Venous Drainage in Pigs Objective: To establish of the model of simultaneous pancreas-kidney tra....
Studys on Brain Imaging of Cerebral Blood Flow and Glucose Metabolism during Inhalant Anesthesia in H

Objective:To investigate the effects of volatile anesthetics on human regional cerebral glucose metabolism and regional cerebral blood flow with brain functional imaging and electrophysiology technology, and explore the main targets that sen....
The Study of Correlative Effect Factors on Atelectasis after General Anesthesia

ObjectiveHypoxemia is a familiar complication during and after operation. According to reports, mild to moderate hypoxemia ( arterial oxygen saturation of between 85% -90% ) occurs in about half of all patients undergoing anesthesia and e-le....
Studies on Susceptibility Genes of Epidemic Iodine Deficiency Disorders

Iodine deficiency is the single most common cause of preventable mental retardation (MR) and brain damage in the world. Iodine deficiency disorders are characterized by MR and the aberrations of T3、T4 and TSH. In China, the Qin-Ba Mountain....
Study on the Abnormalities of Bone Marrow Hematopoietic Stem Cell or Progenitor Cell and Immunoregula

Systemic lupus erythematosus (SLE) is a chronic, multisystem autoimmune disease with unclear pathogenesis, which can not be cured by regular medicine therapy. As the bone marrow transplant developing, the idea, which SLE is a stem cell disea....
Clinical and Experimental Study of Recombinant Human-murine Chimeric Anti-TNF Monoclonal Antibody (In

Part I: Clinical Study of Loading Regimen Infliximab in Active Ankylosing SpondylitisObjective: (1) To evaluate the efficacy and safety of a loading regimen of the anti-tumour necrosis factor (TNF)-a antibody infiiximab in ankylosing spondyl....
Study of Candidate Gene in Ankylosing Spondylitis of Han Chinese

The location of tumor necrosis factor-alpha gene (TNFa) at a susceptibility locus for ankylosing spondylitis (AS) on chromosome 6p21.3, has been identified by several linkage studies across multiple population groups. In the light of these f....
Gene Therapy for Rheumatoid Arthritis by Adeno-associated Virus/sTNFRⅡ: Fc

Rheumatoid arthritis (RA) is a chronic systemic autoimmune inflammatory disease of unknown etiology. Cytokines network plays an important role in RA pathological process is generally accepted. Tumor necrosis factor α (TNF α ) is a multifuc....
Role of DDR2 in Pathogenesis of Rheumatoid Arthritis

Rheumatoid Arthritis (RA) is an autoimmune disease manifesting as chronic and symmetric arthritis. Many factors are involved in the pathogenesis of RA including immune cells, cytokines and proteases. DDR2 is a recently identified receptor ty....
The Importance of the Abnormalities of Thymus and T-Cell Differentiation in the Pathogenesis of Syste

Systemic lupus erythematosus (SLE) is a specific auto-immune disease associated with various factors, and its pathogenesis is too complex to completely elucidate. T cell abnormalities and abnormal production of cytokines is a key event of B....
CCR4 Expression on Circulating CD4+T Cells in Rheumatic Diseases

IntroductionChemokines are a large superfamily of chemotactic cytokines characterized as small peptides that induce chemotactic migration of leukocytes. CC chemokines are chemotactic for lymphocytes, monocytes, eosinophiles, and basophils. S....
Part one Correlations between 4G/5G Polymorphism in PAI-1 Gene Promotor Region and Type 2 Diabetes Va

Objective:The aim of this study is to disclose the PAI-1 genotype, alleles distribution features in obese type 2 diabetic patients of northern China Han nationality and their relationships between the body composition, insulin sensitivity an....
Association between Uncoupling Protein 2 Gene Polymorphisms and Obesity in Japanese

Body weight in humans appears to be a trait with strong genetic determinants and for adult body weight heritability is estimated to be between 50% and 80%. As it well known, obesity is presumed to develop when there is an imbalance between e....
Study on the Differentiation of MSCs and Effect of MSCs with rAAV-GDNF on the Function Recovery of Sp

Part Ⅰ: The isolation, culture of the MSCs and study on theirbiological features in vitroObjective: To isolate MSCs from rat bone marrow, then culture and identify the obtained cells by detecting it's biological features and ultrastructure....
Changes in Serum Elements of Rabbits After Spinal Cord Injury and Their Clinical Significance

Objective A graded contusion spinal cord injury (SCI) model was made by weight drop technique (modified Allen's method). The contents of major element calcium (Ca), Magnesium (Mg) and trace elements Copper (Cu), Zinc (Zn) and Iron (Fe) were....
Experimental Study of Repairment of Rat Spinal Cord Injuries Using Activated Macrophages Transplantat

Background: Spinal cord injury (SCI) leads to an irreversible loss of motor and sensory functions below the level of injury due to the poor ability of the cell bodies to regenerate new axons and inhibitory acting for the myelin or the format....
The Experimental Research of Motor and Somatosensory Evoked Potentials on Spinal Cord Injury

Objective: Evoked potentials have been used both experimentally and clinically to study the function of the spinal cord.The purpose of this study was to evaluate the validity and feasibility of somatosensory evoked potentials(SEP) and transc....
The Experimental Study of Bone Marrow Stromal Cells Transplantation in Spinal Cord Injury

PrefaceExperimental evidences have shown that bone marrow stromal cells ( BMSCs ) , when transplanted into the injured spinal cord of rats, promote functional recovery. Bone marrow stromal cells survived after transplantation and appeared to....
Experimental Study of the Repairing Effect of Acellular Nerve Allografts with Cultured Schwann Cells

Great progress was made on the study of injury and rehabilitating of peripheral nerve by tissue engineering in the recent years. The use of an artificial nerve conduit containing viable Schwann cells (SCs) is one of the most promising approa....
Morphology of Experimentally Denervated and Reinnervated Guinea Pigs Facial Nerve and Facial Muscles

IntroductionA motor neuron and the skeletal muscles controled by the neuron constitute a motor unit . Each part of the motor unit is important for the unit and the integrality of the motor unit's structure is the foundation of its physical f....
The Transfection with GFP Gene and the Differentiation of Bone Marrow Stroma Cells into Neuron-like i

Objective To study the isolation, purification, amplification and biological character of mesenchymal stem cells ( BMSC) form rat bone marrow. To study the possibility that transforming growth factor - β、 nerve growth factor and the traum....
The Study of the Mechanism of Spinal Cord Injury and the Effect of Adenovirus-mediated GDNF Transfer

The treatment of spinal cord injury is a problem that puzzled the orthopaedic scientists. The extent of initial damage to the spinal cord produced by a spinal cord injury depends on factors such as the mechanism of injury, force of the impac....
Expeimental Study on Adenoviral-Mediated Exogenous Genes Expression in Spinal Cords and Peripheral Ne

Injuries of peripheral nerves have long been a common clinical problem. Sophisticated microsurgery skills have made neurorrhaphy precise, however, the functional recovery of injured nerve is unsatisfactory up to the present, for peripheral n....

End