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Basic and Clinical Research on Preventing Restenosis with Intravascular Radiation After Angioplasty
Percutaneous transluminal coronary angioplasty (PTCA) has an established role as a nonsurgical catheter-based treatment for coronary artery disease at present, but restenosis (RS) appreciably limits its long-term effect. Objectives:We design....
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Study on the Clinical Risk Factors, Polymorphism of Lipoprotein Lipase Gene and Its Post-heparin Plas
Background Despite remarkable successes in the treatment and prevention of coronary heart disease(CHD) in the past decades,it is still one of the leading causes of death and premature disability in the world .There is a rising trend accordin....
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Circle of Willis: Morphologic Variation in Normal Chinese Population and Its Relationship to Ischemic
The vessles can be displayed by MR angiography without contrast medium, after contrast administration with higher dose than routine the vascular contrast especially in the small vessles would be improved. But what about the lower dose ? Trsh....
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Neuro-vascular Region of Lateral Skull Base: Imageo-anatomic Study by Multi-slice CT and High Field M
Part I: Neuro-vascular region of lateral skull base: anatomic study on dissectionsPurpose: To observe and analysis the neuro-vascular region of lateral skull base by morphologic anatomy, including location, morphology, size and neighbor stru....
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Experimental Study and Clinical Application of Integrated Three-dimensional Ultrasound
Objective To evaluate the significance of experimental study and clinical application of integrated three-dimensional ultrasound(3-d US). Material and Methods VX2 liver tumors of the New Zealand white rabbits in vivo were observed with 3-d u....
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Experimental Study of Evaluation of Vascular Remodeling With Doppler Ultrasound Measuring Shear Stres
Cytological experiments demonstrate that physiological and elevated shear stress can inhibit the formation of atherosclerotic plaque by protecting endothelial cells, but oscillatory or lower shear stress may accelerate atherosclerosis by inj....
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Multi-dimensional Multi-parametrical Functional Reconstruction of Ultrasound Heart Images
The accurate diagnosis and efficient treatment of cardiopathy is of great social significance. But traditional three-dimensional ultrasound reconstruction system can just depict three-dimensional anatomical structure,so it's very difficult t....
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DOCTORAL THESIS Basic and Clinical Research of MRS and MRI in Reperfused-ischemic Myocardium
Magnetic resonance spectroscopy (MRS) is a method for non-invasive detection of various aspects of cardiac metabolism in humen. The MR spectroscopic technique allows for study of a number of nuclei, such as 1H, 13C, 19F, 23N, 31P and 39K. At....
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The Anatomic and MR Imaging Study of the Uncommon Ligamentous and Tendinous Structures of the Normal
The uncommon ligamentous and tendinous structures(ULTS)of the knee include the ligamentous and tendinous structures except for the bigger structures, such as the cruciate ligaments, the tendon of the quadriceps lemons muscle and patellar ten....
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Resistance Mediated by AmpC β-Lactamase and ESBLs in Enterobacter Cloacae
[OBJECTIVE] To investigate the rates of occurrence of high-level AmpC P -lactamase producers and ESBL-producers among clinical isolates of Enterobacter cloacae. To establish a convenient method for detecting resistance mediated by high-level....
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Development of Helicobacterpylori immunochip diagnosis system
Helicobacter pylori (H. pylori} chronically infects up to 50% of the world's human population, responsible for chronic gastritis, peptic ulcer disease, gastric cancer and gastric mucosa-associated lymphoid tissue (MALT) lymphoma in humans. A....
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Experimental Study of CD34～+ Cell Mixed with TK～+T Lymphocyte Transduced TK Gene Transplantation
Experimental study on CD34+ cell mixed with TK+T lymphocyte transduced TK gene transplantation for treatment of graft-vurses-host disease and preservation of graft-vurses-leukemia effects in H~2 haploidentical murine modelsA great deal of ac....
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Study of Ly49A Expression in T Lymphocytes and Its Regulation in Mouse Acuse Acute Graft-Versus-Host
Hematopoietic stem cell transplantation (HSCT) provides a curative therapy for patients with hematological malignancies and some refractory non-hematological diseases but even when the donor and recipient are major histocompatibility complex....
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Study on the Extended-Spectrum β-Lactamases Genes and the Properties of a Novel SHV β-Lactamase
Extended-spectrum (3-lactamases (ESBLs) which is a large species of P-lactamases can hydrolyze the third generation of cephalosporins and monobactams. ESBLs are mainly produced by Klebsiella pneumoniae and Escherichia coli. In the last decad....
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The Characterization and Implications of Dendritic Cells and Interferon-producing Cells in Patients w
Dendritic cells (DCs), the most potent professional antigen processing cells (APC) in vivo, play a crucial role in human immune system. DCs activate host immune response not only by their capturing and processing antigens to MHC-I and II mol....
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Influence of Dendritic Cell in the Pathogenesis of Chronic Viral Hepatitis
PARTIIn vitro Culture of Dendritic Cell Induced from Peripheral Blood MonocyteDendritic cell (DC) is important for the elimination of pathogens such asvirus, bacteria or parasites. And DC is also prospective in the gene therapy of tumor or i....
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A Study on CTL clone with specificity of Hantaan virus nucleocapsid protein from peripheral blood of
Hemorrhagic Fever with Renal Syndrome(HFRS) is an acute infectious disease caused by HV infection. It is characterized with high fever, bleeding and kidney damage. Hantaan virus, the prototype member of the Hantavirus genus, causes hemorrhag....
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Study of Molecular Epidemiology of HIV and Mechanism of Anti-HIV Phenomena Due to Coreceptor Mutation
AIDS is a kind of severe disease caused by human immunodeficiency virus(HIV). It has the characteristic of high death rate, high spreading speed and causing grave damage. HIV is divided into two types, HIV-1 and HIV-2, and AIDS is mainly cau....
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The Relationship between 24-hour Ambulatory Diastolic Blood Pressure, Pulse Pressure and Cardiovascul
Objective The goal of this study was to investigate the relationship between ambulatory diastolic blood pressure levels and cardiovascular risk in the elderly men with treated essential hypertension. Methods The study population consisted of....
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The Relationship between Mannose-binding Lectin (MBL) and Rheumatic Heart Disease and Recombinant MBL
BackgroundRheumatic heart disease (RHD) is one of the classic diseases that are affected by environmental and individual factors. Itself is one of the sequela of acute rheumatic fever (ARF) in adolescence and ARF is induced by the infection....
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Experimental Study of Prevention of Restenosis in Coronary Stents
PURPOSEAnimal and clinical studies using radioactive 32P stents have showed largely disappointing results for its high rate of edge restenosis . In contrast, a short half-life, high dose-rate ^Y ft emitting stents more closely mimics the del....
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Prevention and Treatment of Stent Restenosis-The Study of Acute Exposure to Heat to Induce Apoptosis
OBJECTIVE: The restenosis is one of the most importent problem which is steel unsovled in the cardiovascular field, though a lot of work on restenosis have been finished. There are no effective method of reducing or curing restenosis can be....
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The Relationship of Chlamydia Pneumoniae and Atherosclerosis
Background Coronary artery disease(CAD) is a major cause of mortality throughout the world. The pathogenesis of CAD is based on the process of atherosclerosis. The accepted risk factors linked to CAD indued dyslipidemia, smoking, hypertensio....
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The studies on mechanism of insulin-like growth factor 1 and neopterin in atherosclerosis and coronar
Objective: Recent, people have found that insulin-like factor 1 (IGF1) system is of more important role in human's pathophysiological progresses. The IGF1 system in cardiovascular system is more relative to atherosclerosis and coronary heart....
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1.Correlation Between Levels of Plasma Homocysteine and Coronary Atherosclerosis and Its Pathogenesis
Correlation Between Levels of Plasma Homocysteine and Coronary Atherosclerosis and Its Pathogenesis MechanismAtherosclerosis is one of the main diseases to threaten human's health for the time being. In many countries, especially in the deve....
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Effectes of Transfection with Antisense Integrin Eukaryotic Vectors and Static Magnetic Field Interve
The study aimed to investigate the roles of two important ECM protein fibronectin, laminin and their receptor integrin alpha5betal in regulating the VSMCs biological behaviors. And using gene blockade by antisense integrin vector transfectio....
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Biologic effects of static magnetic field on vascular endothelial cells
Percutaneous transluminal coronary angioplasty (PICA) and stent implantation are the breakthrough of therapy of coronary artery disease in past two decades, but restenosis after the procedure is still the main problem affecting the outcoming....
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Experimental Study of Co-expression of Double Genes for Preventing Arterial Restenosis
With the incidence rate of atherosclerosis growing, it has been become the main causes of mortality and morbidity in our country. The treatment of symptomatic coronary stenosis by percutaneous transluminal coronary angioplasty (PTCA) is wide....
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The Significance of Plasmainterleukin-8 Variety in Patients with Coronary Heart Disease Pre-And Pro-C
Coronary heart disease (CHD) has been the first critical disease of human being around the world. Percutaneous coronary intervention (PCI) has established an effective procedure for CHD. However, there were still some problems contributed to....
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Animal and Clinical Study of the Predictive Value of Ultrasonic Tissue Characterization, Color Kinesi
Objective1. To assess the value of ultrasonic tissue characterization with integrated backscatter(IBS) and color kinesis (CK) on viable myocardium of swine with chronic coronary artery stenosis and collateral circulation development.2. To as....