The structure of the pile-anchor system ,which are combined of prestressed anchor-rope and Anti-sliding pile , is one of the most effective reinforced structures, it is used wildly in some slop protection works. Anti-sliding pile especially the pile with prestressed anchor cable and the foundation beam with prestressed anchor cable including the single beam and the frame, are the new pattern structures of the pile-anchor system that have been widely used in the slide-resistant engineering. Through the utilization, it can produce stronger Anti-sliding action. The combined structure can utilize the latent energy of rock or soil mass. What's more, because the structure is simple, beautiful and economical, it has well economic and technology value. But now, designing theory of these structures are delayed greatly than their applications. it is an emergent work to study the designing theory and establish specifications.On the basis of the important research project of Beijing-Zhuhai highway and Sichuan-Xizang highway, the thesis developed the structure's design theory. First, the computation theory of the anti-sliding pile has been researched including interaction between the pile and the landslide, the mechanical model and the calculation method of pile-anchor system. Second, the internal force status, the mechanical computation model and the design method of the foundation beam with prestressed anchor cable have been analyzed. Third, a new coupling of long-term prestress loss of anchor tie and slope creep mode is built and the theoretical function of long-term prestress variation is put forward. Last, slope risk analysis are researched. The main results and conclusions gained can be expressed as follows.1. Aiming at the existing problems in the method for computing anti-sliding pile with prestressed anchoring cable, an improved method is proposed in this paper. According to the actual construction process and mechanical condition of the pile and the prestressed anchoring cable, the internal force of the structure should be computed in two steps. Firstly, the pile under the prestress of the anchoring cable and a part of sliding thrust will be taken into account in